jo0353381_si_001.pdf (223.03 kB)
New Efficient Procedure for the Use of Diethoxyphosphoryl as a Protecting Group in the Synthesis of Polyazamacrocycles. Preparation of Polyazacyclophanes Derived from Resorcinol
journal contribution
posted on 2003-12-26, 00:00 authored by M. Isabel Burguete, Laura López-Diago, Enrique García-España, Francisco Galindo, Santiago V. Luis, Juan F. Miravet, Dariusz SroczynskiThe synthesis of polyazamacrocycles containing
an electron-rich aromatic subunit derived from resorcinol
is described. The reported synthetic procedure is based on
the use of diethoxyphosphoryl (Dep) as an amine protecting
group. The new conditions employed for the cyclization
reaction allow for a generalized use of Dep in the synthesis
of polyazamacrocycles.