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New Approach to the Stereoselective Synthesis of Metalated Dienes via an Isomerization−Elimination Sequence

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journal contribution
posted on 08.08.2002, 00:00 by Nicka Chinkov, Swapan Majumdar, Ilan Marek
Treatment of Cp2ZrBu2 with enol ether containing a remote double bond lead to conjugated metalated diene as single isomer via a tandem isomerization−elimination sequence. 2-Arylsulfonyl 1,3-dienes can also be used as a source of dienyl zirconocene derivatives, and the stereochemistry of the diene is dependent on the transmetalation reaction.