Nanocomposite-Coated
Microfluidic-Based Photocatalyst-Assisted
Reduction Device To Couple High-Performance Liquid Chromatography
and Inductively Coupled Plasma-Mass Spectrometry for Online Determination
of Inorganic Arsenic Species in Natural Water
posted on 2017-05-01, 00:00authored byCheng-Hsing Lin, Yu Chen, Yi-An Su, Yu-Ting Luo, Tsung-Ting Shih, Yuh-Chang Sun
To selectively and
sensitively determine the trace inorganic As
species, As(III) and As(V), we developed a nanocomposite-coated microfluidic-based
photocatalyst-assisted reduction device (PCARD) as a vapor generation
(VG) device to couple high-performance liquid chromatography (HPLC)
separation and inductively coupled plasma-mass spectrometry (ICPMS)
detection. Au nanoparticles were deposited on
TiO2 nanoparticles to strengthen the conversion efficiency
of the nanocomposite photocatalytic reduction. The sensitivity for
As was significantly enhanced by employing the nanocomposite photocatalyst
and using prereduction and signal-enhancement reagents. Under the
optimal operating conditions, the analytical detection limits (based
on 3σ) of the proposed online HPLC/nanocomposite-coated microfluidic-based
PCARD/ICPMS system for As(III) and As(V) were 0.23 and 0.34 μg·L–1, respectively. The results were validated using a
certified reference material (NIST SRM 1643e) and groundwater sample
analysis, indicating the good reliability and applicability of our
proposed system for the determination of inorganic As species in natural
fresh water.