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NaI-Mediated Acetamidosulphenylation of Alkenes with Nitriles as the Nucleophiles: A Direct Access to Acetamidosulfides

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journal contribution
posted on 06.11.2015, 00:00 by Yang Zheng, Yue He, Guangwei Rong, Xiaolu Zhang, Yuecheng Weng, Kuiyong Dong, Xinfang Xu, Jincheng Mao
An example of a transition-metal-free, direct, and efficient acetamido­sulphenylation reaction of alkenes using nitriles as the nucleophiles via a radical process is presented. This reaction shows a broad substrate scope and high regioselectivity and provides straightforward access to acetamidosulfide derivatives in moderate to high yields.