Multipoint Recognition of Basic Proteins at a Membrane Model
journal contributionposted on 2004-06-30, 00:00 authored by R. Zadmard, M. Arendt, T. Schrader
Cell surface recognition achieves high efficiency and specificity because of its polyvalent nature. A biomimetic model has been designed, which consists of a stearic acid monolayer with embedded calixarene tetraphosphonate receptor molecules. This system is able to distinguish between proteins of varying pI at nanomolar concentrations.