American Chemical Society
ja049191m_si_001.pdf (1.27 MB)

Multipoint Recognition of Basic Proteins at a Membrane Model

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journal contribution
posted on 2004-06-30, 00:00 authored by R. Zadmard, M. Arendt, T. Schrader
Cell surface recognition achieves high efficiency and specificity because of its polyvalent nature. A biomimetic model has been designed, which consists of a stearic acid monolayer with embedded calixarene tetraphosphonate receptor molecules. This system is able to distinguish between proteins of varying pI at nanomolar concentrations.