Multicomponent-Multicatalyst Reactions (MC)2R: Efficient Dibenzazepine Synthesis

Tsoung, Jennifer; Panteleev, Jane; Tesch, Matthias; Lautens, Mark

doi:10.1021/ol4030925.s002

ol4030925_si_002.pdf (2.8 MB)

Multicomponent-Multicatalyst Reactions (MC)²R: Efficient Dibenzazepine Synthesis

journal contribution

posted on 2014-01-03, 00:00 authored by Jennifer Tsoung, Jane Panteleev, Matthias Tesch, Mark Lautens

A Rh^I/Pd⁰ catalyst system was applied to the multicomponent synthesis of aza-dibenzazepines from vinylpyridines, arylboronic acids, and amines in a domino process with no intermediate isolation or purification.

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Keywords

vinylpyridine arylboronic acids Efficient SynthesisA RhI domino process amines multicomponent synthesis catalyst MC isolation purification Dibenzazepine

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