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Mizoroki–Heck Reaction of (1-Fluorovinyl)methyldiphenylsilane with Aryl Iodides

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posted on 2011-10-21, 00:00 authored by Kensuke Hirotaki, Takeshi Hanamoto
The Mizoroki-Heck reaction of (1-fluorovinyl)methyldiphenylsilane with a variety of aryl iodides was accomplished under the conditions composing Pd(OAc)2, Ag2CO3 and MS 4 Å in 1,4-dioxane to give the corresponding (E)-β-aryl-(α-fluorovinyl)methyldiphenylsilanes with excellent stereoselectivity.

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    The Journal of Organic Chemistry

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