Microwave-Assisted Regioselective
Addition of P(O)−H Bonds to Alkenes
without Added Solvent or Catalyst

Stockland,, Robert A.; Taylor, Ross I.; Thompson, Laura E.; Patel, Priti B.

doi:10.1021/ol0474047.s001

ol0474047_si_001.pdf (9.3 MB)

Microwave-Assisted Regioselective Addition of P(O)−H Bonds to Alkenes without Added Solvent or Catalyst

journal contribution

posted on 2005-03-03, 00:00 authored by Robert A. Stockland,, Ross I. Taylor, Laura E. Thompson, Priti B. Patel

The addition of P(O)−H bonds to alkenes has been accomplished using microwave irradiation in the absence of added solvent and catalyst. In addition to single addition reactions, tandem hydrophosphinylation reactions with alkynes afforded unsymmetrical species such as phosphine oxide − phosphinates.