MgO/CaO Nanocomposite Facilitates Economical Production of d‑Fructose and d‑Allulose Using Glucose and Its Response Prediction Using a DNN Model
journal contributionposted on 2022-02-03, 01:13 authored by Senthil M. Arumugam, Dalwinder Singh, Sangeeta Mahala, Bhawana Devi, Sandeep Kumar, Sunaina Jakhu, Sasikumar Elumalai
This study presents a method for the economical production of fructose and allulose (a valuable byproduct) directly from glucose over a MgO/CaO nanocomposite under an aqueous condition. The catalyst containing MgO and CaO at equal proportions helped manipulate the inherent characteristics of CaO, particularly strong basicity and surface properties. The analytical characterizations revealed that the structural assembly is such that MgO settles at the surface to initiate the isomerization reaction by providing a higher number of weak/medium base sites. The CaO present beneath undertakes the sequential conversion of the enol-intermediate to ultimate fructose and byproducts (mannose and allulose). Thus, the catalyst accelerated the glucose interconversion to obtain a fructose yield as high as 33 wt % with 80% selectivity within 15 min. At the same time, it also initiated the C-3 fructose epimerization to yield allulose (a low-calorie sugar molecule). Moreover, the adopted deep neural network modeling well predicted the catalytic response with the MAE <5%. The technoeconomic analysis estimated the minimum selling price of different products to be US $ ∼4/kg (fructose), $ ∼4/kg (mannose), and $ ∼10/kg (allulose).
technoeconomic analysis estimatedparticularly strong basicityminimum selling pricemedium base sitesanalytical characterizations revealedresponse prediction using3 fructose epimerizationcatalyst containing mgocatalytic responsecatalyst accelerated∼ 4∼ 10‑ fructosevaluable byproductultimate fructosestudy presentsstructural assemblysequential conversionmgo settlesisomerization reactioninherent characteristicshigher numberfructose yieldfructose ),economical productiondnn modeldifferent productsaqueous conditionalso initiated5 %.33 wt