ja305801m_si_001.pdf (1.5 MB)
Metal-Free Oxidative Trifluoromethylthiolation of Terminal Alkynes with CF3SiMe3 and Elemental Sulfur
journal contribution
posted on 2012-08-01, 00:00 authored by Chao Chen, Lingling Chu, Feng-Ling QingA metal-free oxidative trifluoromethyl-thiolation
of terminal
alkynes using readily available CF3SiMe3 and
elemental sulfur at room temperature has been developed. This reaction
provides an efficient and convenient method for the preparation of
alkynyl trifluoromethyl sulfides bearing a wide range of functional
groups. Preliminary investigation revealed that elemental sulfur instead
of air acted as the oxidant.