A novel and environmentally
attractive C(sp3)–H
azidation of 2-oxindoles involving the formation of a C–N bond
was developed. This methodology achieved for the first time 3-azido-2-oxindole
construction under metal-free conditions at room temperature via a
radical strategy. PhI(OAc)2 was used as the oxidant and
Et3N was used as the additive in this transformation. Furthermore,
the mechanistic study indicated that this azidation involved a radical
process.