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Download fileMagneto-Controlled Enzyme Activity with Locally Produced pH Changes
journal contribution
posted on 2021-03-08, 12:33 authored by Krisztina Szekeres, Paolo Bollella, Yongwook Kim, Sergiy Minko, Artem Melman, Evgeny KatzBiocatalytic
activity of amyloglucosidase (AMG), immobilized on
superparamagnetic nanoparticles, is dynamically and reversibly activated
or inhibited by applying a magnetic field. The magnetic field triggers
aggregation/deaggregation of magnetic particles that are also functionalized
with urease or esterase enzymes. These enzymes produce a local pH
change in the vicinity of the particles changing the AMG activity.