ol5b01307_si_001.pdf (846.26 kB)
Download fileMachines vs Malaria: A Flow-Based Preparation of the Drug Candidate OZ439
journal contribution
posted on 2015-12-22, 22:41 authored by Shing-Hing Lau, Alicia Galván, Rohan
R. Merchant, Claudio Battilocchio, José A. Souto, Malcolm
B. Berry, Steven V. LeyAn
efficient preparation of the antimalarial drug candidate OZ439,
which was obtained by integrating a machine-assisted approach with
batch processes, is reported. This approach allows a rapid and cost-effective
production of the key intermediates that were readily elaborated into
the target molecule.
