posted on 2017-11-09, 14:18authored byLía
S. Valencia-Chan, Isabel García-Cámara, Luis W. Torres-Tapia, Rosa E. Moo-Puc, Sergio R. Peraza-Sánchez
Three new lupane-type triterpenes,
3α,24-dihydroxylup-20(29)-en-28-oic
acid (1), 3α,23-dihydroxy-30-oxolup-20(29)-en-28-oic
acid (2), and 3α,23-O-isopropylidenyl-3α,23-dihydroxylup-20(29)-en-28-oic
acid (3), together with eight known compounds (4–11) were isolated from a methanol extract
of Phoradendron vernicosum aerial parts. The chemical
structures of 1–3 were determined
on the basis of spectroscopic data interpretation. The isolated compounds
were tested against seven human cancer cell lines and two normal cell
lines.