posted on 2019-11-19, 15:09authored byYi Gan, Wei Xu, Yuanhong Liu
The first Ni/Cu-catalyzed regiodivergent synthesis of
allylsilanes
directly from allylic alcohols through modulating the steric and electronic
properties of the ligands on the nickel catalyst has been developed.
Good yields and excellent selectivity were obtained regardless of
whether linear or α-branched allylic alcohols were utilized.
Mechanistic studies indicate that an allyloxyboronate species is formed
during the reaction, which likely serves as an activated intermediate
toward the oxidative addition of the C(allyl)–O bond.