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Langmuir Films of Layered Nanomaterials: Edge Interactions and Cell Culture Applications
journal contribution
posted on 2020-08-07, 15:41 authored by Rhiannon W. Harries, Christopher J. Brown, Sean P. Ogilvie, Matthew J. Large, Aline Amorim Graf, Keiran Clifford, Thomas Simon, Georgios Giamas, Alan B. Dalton, Alice A. K. KingThe application of
nanomaterials in technology is limited by challenges
in their processing into macroscopic structures with reliable and
scalable methods. Herein, it is demonstrated that using scalable fabrication
methods such as liquid-phase exfoliation, it is possible to produce
dispersions of a wide variety of layered nanomaterials, including
the first demonstration of boron nitride, with controllable and standardized
size and thickness scaling. These can be used, as-produced, for Langmuir
deposition, to create single layer films with tuneable density. Of
particular importance, we show that the difference in edge chemistry
of these materials dictates the film formation process, and therefore
can be used to provide a generic fabrication methodology that is demonstrated
for various layered nanomaterials, including graphene, boron nitride,
and transition metal dichalcogenides. We show that this leads to controllable
cancer cell growth on graphene substrates with different edge densities
but comparable surface coverage, which can be produced on a statistically
relevant cell study amount. This opens pathways for the generic fabrication
of a range of layered nanomaterial films for various applications
toward a commercially viable film fabrication technology.