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Isoxazolone Based Inhibitors of p38 MAP Kinases

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journal contribution
posted on 24.04.2008, 00:00 by Stefan A. Laufer, Simona Margutti
SAR of N-alkylated isoxazolones as p38 MAP kinase inhibitors was realized. The data herein show the possibility of transferring the SAR study and evaluation from N-1-substituted imidazole to isoxazolones. Optimization of substituent was realized.

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