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Isoprenylated Flavonoids and Adipogenesis-Promoting Constituents from Morus nigra

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journal contribution
posted on 25.04.2011, 00:00 by Xiao Hu, Jin-Wei Wu, Xiao-Dong Zhang, Qin-Shi Zhao, Jian-Ming Huang, He-Yao Wang, Ai-Jun Hou
Ten new isoprenylated flavonoids, nigrasins A−J (110), and three known compounds were isolated from the twigs of Morus nigra. Compounds 8 and 9 promoted adipogenesis, characterized by increased lipid droplet and triglyceride content in 3T3L1 cells, and induced up-regulation of the expression of adipocyte-specific genes, aP2 and GLUT4.