Isoprenylated Flavonoids and Adipogenesis-Promoting Constituents from Morus nigra

Hu, Xiao; Wu, Jin-Wei; Zhang, Xiao-Dong; Zhao, Qin-Shi; Huang, Jian-Ming; Wang, He-Yao; Hou, Ai-Jun

doi:10.1021/np100907d.s001

Isoprenylated Flavonoids and Adipogenesis-Promoting Constituents from Morus nigra

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posted on 2011-04-25, 00:00 authored by Xiao Hu, Jin-Wei Wu, Xiao-Dong Zhang, Qin-Shi Zhao, Jian-Ming Huang, He-Yao Wang, Ai-Jun Hou

Ten new isoprenylated flavonoids, nigrasins A−J (1−10), and three known compounds were isolated from the twigs of Morus nigra. Compounds 8 and 9 promoted adipogenesis, characterized by increased lipid droplet and triglyceride content in 3T3L1 cells, and induced up-regulation of the expression of adipocyte-specific genes, aP2 and GLUT4.

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4.GLUT isoprenylated flavonoids Morus nigra aP 2 3 T 3L cells Compounds 8 nigrasin Constituent adipogenesi lipid droplet Isoprenylated Flavonoids compound Morus nigraTen twigs triglyceride content gene expression

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Isoprenylated Flavonoids and Adipogenesis-Promoting Constituents from Morus nigra

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