American Chemical Society
om9b00393_si_001.pdf (1.71 MB)

Iron(II)-Catalyzed Hydroamination of Isocyanates

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journal contribution
posted on 2019-10-07, 19:43 authored by Amy J. South, Ana M. Geer, Laurence J. Taylor, Helen R. Sharpe, William Lewis, Alexander J. Blake, Deborah L. Kays
A two-coordinate Fe­(II) m-terphenyl complex acts as a precatalyst for the hydroamination of isocyanates, affording urea and biuret derivatives, with product selectivity accomplished via modification of the reaction conditions. Using a more nucleophilic amine facilitates the insertion of up to four isocyanates into the N–H bond, affording triuret and tetrauret derivatives.