ol040036m_si_001.pdf (986.04 kB)
Intramolecular Iron-Mediated Diene/Olefin Cyclocoupling: Formation of Carbon Spirocycles
journal contribution
posted on 2004-07-22, 00:00 authored by Anthony J. Pearson, Xiaolong Wang, Ismet B. DorangeA short and convenient diastereoselective synthesis of all-carbon spirocylic molecules was developed. A straightforward protocol that involves
rearrangement of the diene−Fe(CO)3 complex followed by cyclization delivers the desired product. The reaction substrates were easily prepared
by reaction of an appropriate nucleophile and a cyclohexadienyl-Fe(CO)3 cation.