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Intramolecular 1,3-Dipolar Cycloadditions of Norbornadiene-Tethered Nitrones

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posted on 30.06.2001, 00:00 by Geoffrey K. Tranmer, William Tam
Efficient routes to the synthesis of norbornadiene-tethered nitrones have been developed, and their intramolecular 1,3-dipolar cycloadditions were studied. The cycloadditions occurred in moderate to good yields for a variety of substrates and were found to be highly regio- and stereoselective, giving single regio- and stereoisomers in most cases.

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