American Chemical Society
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Intermolecular Cross-Double-Michael Addition between Nitro and Carbonyl Activated Olefins as a New Approach in C−C Bond Formation

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journal contribution
posted on 2007-10-25, 00:00 authored by Xiaohua Sun, Sujata Sengupta, Jeffrey L. Petersen, Hong Wang, James P. Lewis, Xiaodong Shi
A novel intermolecular cross-double-Michael addition between nitro and carbonyl activated olefins has been developed through Lewis base catalysis. The reaction took place with a large group of β-alkyl nitroalkenes and α,β-unsaturated ketone/esters, producing an allylic nitro compound in good to excellent yields.