American Chemical Society
ol9019277_si_001.pdf (3.92 MB)

Inter- and Intramolecular Addition Reactions of Electron-Deficient Alkenes with Alkyl Radicals, Generated by SET-Photochemical Decarboxylation of Carboxylic Acids, Serve as a Mild and Efficient Method for the Preparation of γ-Amino Acids and Macrocyclic Lactones

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journal contribution
posted on 2009-10-15, 00:00 authored by Yasuharu Yoshimi, Miho Masuda, Tomoyuki Mizunashi, Keisuke Nishikawa, Kousuke Maeda, Nobumasa Koshida, Tatsuya Itou, Toshio Morita, Minoru Hatanaka
Inter- and intramolecular additions of alkyl radicals, generated by SET photochemical decarboxylation reactions of free carboxylic acids, to electron-deficient alkenes take place under mild conditions as part of efficient routes for the formation of N-Boc γ-amino acids and macrocyclic lactones.