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Indium-Mediated Reduction of Hydroxylamines to Amines

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journal contribution
posted on 2003-04-22, 00:00 authored by Stefano Cicchi, Marco Bonanni, Francesca Cardona, Julia Revuelta, Andrea Goti
A novel and simple procedure for reduction of hydroxylamines to the corresponding amines by means of indium powder in aqueous media is reported. Applicability to one-pot reactions and isoxazolidine N−O bond reduction is also demonstrated. A catalytic version of the process using 2−5% In in the presence of other metals (Zn, Al) has been successfully developed.

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