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In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines

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journal contribution
posted on 2001-05-05, 00:00 authored by Leonie Blackburn, Richard J. K. Taylor
Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation−imine formation−reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

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