In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines
journal contributionposted on 05.05.2001, 00:00 by Leonie Blackburn, Richard J. K. Taylor
Manganese dioxide is employed as an in situ oxidant for the one-pot conversion of alcohols into imines. In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation−imine formation−reduction sequence is reported. This procedure enables alcohols to be converted directly into both secondary and tertiary amines.