In(III)-Mediated Chemoselective Dehydrogenative Interaction of ClMe2SiH with Carboxylic Acids: Direct Chemo- and Regioselective Friedel−Crafts Acylation of Aromatic Ethers
journal contributionposted on 2007-02-01, 00:00 authored by Srinivasarao Arulananda Babu, Makoto Yasuda, Akio Baba
Chemoselective dehydrogenative interaction of ClMe2SiH with a carboxylic acid group in the presence of InX3 is reported. 13C NMR investigation revealed the formation of PhCOOSi(Cl)Me2 as the major transient intermediate. Chemo- and regioselective Friedel−Crafts acylation of aromatic ethers directly from carboxylic acids was established.