posted on 2024-04-03, 17:41authored byRahul
Kumar Saini, Paran J. Borpatra, Trayambek Nath Chaubey, Satyendra Kumar Pandey
An I2-mediated approach
for selective C–H
functionalization
of unprotected aniline derivatives for synthesizing benzils and quinoxaline
derivatives from sulfoxonium ylides has been described. Aniline derivatives
and sulfoxonium ylides ornamented with different functional groups
showed good compatibility. They afforded the corresponding products
with moderate to high yields via a mild and simple procedure. Finally,
we validated the practicality of this method by scaling up the reaction
and further conversion of the synthesized derivatives into other valuable
molecules.