American Chemical Society
ol5b01933_si_001.pdf (6.19 MB)

I2‑Catalyzed C–O Bond Formation and Dehydrogenation: Facile Synthesis of Oxazolines and Oxazoles Controlled by Bases

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journal contribution
posted on 2015-08-07, 00:00 authored by Wen-Chao Gao, Fei Hu, Yu-Ming Huo, Hong-Hong Chang, Xing Li, Wen-Long Wei
A general method for the synthesis of oxazolines and oxazoles was developed through I2-catalyzed C–O bond formation and dehydrogenation with the same oxidant, TBHP. By simply tuning reaction bases, either oxazolines or oxazoles were selectively produced from β-acylamino ketones.