American Chemical Society
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Highly Enantioselective Synthesis of Tetrahydro-β-Carbolines and Tetrahydro-γ-Carbolines Via Pd-Catalyzed Intramolecular Allylic Alkylation

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journal contribution
posted on 2006-02-08, 00:00 authored by Marco Bandini, Alfonso Melloni, Fabio Piccinelli, Riccardo Sinisi, Simona Tommasi, Achille Umani-Ronchi
A novel Pd-catalyzed intramolecular allylic alkylation of indoles allows THBCs and THGCs to be effectively synthesized in high yields and excellent enantiomeric excesses (ee up to 97%).