American Chemical Society
ol0352963_si_002.pdf (2.21 MB)

Highly Enantioselective Catalytic Phenylation of Ketones with a Constrained Geometry Titanium Catalyst

Download (2.21 MB)
journal contribution
posted on 2003-09-06, 00:00 authored by Celina García, Patrick J. Walsh
The catalytic asymmetric addition of phenyl groups from diphenylzinc to ketones is reported. The catalyst, generated from a dihydroxy bis(sulfonamide) ligand and titanium tetraisopropoxide, gives good to excellent enantioselectivities with a range of substrates.