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Highly Enantioselective Additions of Diethylzinc to Aldehydes Using 2-Triflamido-methyl-2‘-hydroxy-1,1‘- binaphthyl

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journal contribution
posted on 13.11.2003, 00:00 by Seung-Wan Kang, Dong-Hyun Ko, Kyoung Hoon Kim, Deok-Chan Ha
A new N-triflated amino alcohol−titanium catalyst was designed for the asymmetric ethylation of aldehydes. This binaphthyl-based sulfonamido alcohol ligand shows uniformly high yield and enantioselectivity in the diethylzinc additions of aromatic, aliphatic, and unsaturated aldehydes.