American Chemical Society
jo0c01084_si_001.pdf (11.32 MB)

High-Yielding Water-Soluble Asymmetric Cyanine Dyes for Labeling Applications

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journal contribution
posted on 2020-07-29, 16:03 authored by Natalia Wolf, Louise Kersting, Christoph Herok, Cornelius Mihm, Juergen Seibel
A simple and efficient microwave-assisted synthesis of asymmetric pentamethine cyanine dyes with various functional groups was developed, which allows high-yielding results. The synthesized dyes are modifiable and suitable for single-molecule imaging in biological and medical sciences by application of click chemistry or classic esterification and amidation.