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Green Progression for Synthesis of Regioselective β-Amino Alcohols and Chemoselective Alkylated Indoles

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journal contribution
posted on 19.11.2010, 00:00 by Boningari Thirupathi, Rapelli Srinivas, Avvari N. Prasad, J. K. Prashanth Kumar, Benjaram M. Reddy
Solid acid catalysts based on zirconia materials were investigated for the first time as catalysts for regioselective organic synthesis under environmentally benign and mild conditions. The novel TiO2−ZrO2 mixed oxide catalyst led to two distinct products by the formation of an N−C bond (β-amino alcohols) and a C−C bond (Friedel−Crafts alkylation).