Green Designer Solvents for Boosting the Extraction of Biocompounds from Eugenia pyriformis Cambess Leaves

This work aimed at evaluating eutectic mixtures as green and designer solvents to extract bioactive compounds from Eugenia pyriformis Cambess (EPC) leaves. First, it was defined through the Folin–Ciocalteu (F–C) reducing capacity and antioxidant activity the optimized conditions of solid–liquid extraction (SLE). Consecutively, this condition (65 °C, 1:30 (m/v) solid–liquid ratio, and 150 min of process) was applied to evaluate the effect of the eutectic mixture-forming compounds in the SLE. The results showed that the lactic acid-based eutectic mixture was the most suitable solvent to preserve bioactive compounds from EPC leaves. Moreover, according to F–C analysis, the lactic acid-based eutectic mixtures boosted the SLE (163.14 ± 5.81 mg gallic acid/g sample). Regarding the phenolic profile, the EPC leaves showed the presence of quercetin, naringin, rutin, catechin, and gallic acid. These findings proved the eutectic mixtures and their forming compounds designer ability to extract valuable biocompounds from EPC leaves.