Gram-Scale Synthesis of 2,5-Difluoro-7,7,8,8-tetracyanoquinodimethane (F₂‑TCNQ)

The molecule 2,5-difluoro-7,7,8,8-tetracyanoquinodimethane (F₂-TCNQ) is an organic semiconductor with many promising properties, including high charge mobility (μ). However, an efficient gram-scale synthesis of F₂-TCNQ has not been fully documented. Herein, we report a synthesis of F₂-TCNQ via a three-step sequence that affords F₂-TCNQ in 58% cumulative yield. This synthesis was used to prepare more than 1 g of F₂-TCNQ.