Gold(I)-Catalyzed Domino Ring-Opening
Ring-Closing Hydroamination of
Methylenecyclopropanes (MCPs) with
Sulfonamides: Facile Preparation of
Pyrrolidine Derivatives
posted on 2006-08-31, 00:00authored byMin Shi, Le-Ping Liu, Jie Tang
Reaction of methylenecyclopropanes 1 with sulfonamides produces the corresponding pyrrolidine derivatives 3 in moderate to good yields
under the catalysis of Au(I) via a domino ring-opening ring-closing hydroamination process.