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Gold(III)-Catalyzed Three-Component Coupling Reaction (TCC) Selective toward Furans

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journal contribution
posted on 07.06.2013, 00:00 by Jian Li, Li Liu, Dong Ding, Jiangtao Sun, Yangxuan Ji, Jialing Dong
An efficient three-component coupling reaction toward a variety of furan derivatives has been developed. This cascade transformation proceeds via the gold-catalyzed coupling reaction of phenylglyoxal derivatives, secondary amines, and terminal alkynes, under the reaction conditions, that undergoes cyclization into the furan core.