ja5b12149_si_001.pdf (898.55 kB)
Generation, Characterization, and Application of Hierarchically Structured Self-Assembly Induced by the Combined Effect of Self-Emulsification and Phase Separation
journal contribution
posted on 2016-02-02, 00:00 authored by Xiuyu Wang, Yi Hou, Li Yao, Mingyuan Gao, Maofa GeHierarchically
structured magnetic single-hole hollow spheres (MSHS)
have been successfully obtained via a facile self-assembly strategy.
This methodology allows the double emulsions generated via the combined
effect of self-emulsification and phase separation to provide confinement
for directing the self-assembly of magnetic nanoparticles (MNPs).
The resulting MSHS fully capitalize on both the multifunctional properties
of MNPs and container features of single-hole hollow spheres. Moreover,
the magnetic properties showed obvious improvement and can be tuned
by modulating the assembled structure. Thus, MSHS can be used as a
smart platform with multiple functionalities including image contrast
enhancement, selective encapsulation for biomacromolecules, on-demand
release, and magnetically guided transport. This strategy is very
promising in the design of hierarchically structured assemblies for
desired applications in biomedicine and other fields.