Gene-Mediated Chemical Communication in Synthetic
Protocell Communities

Tang, T-Y. Dora; Cecchi, Dario; Fracasso, Giorgio; Accardi, Davide; Coutable-Pennarun, Angelique; Mansy, Sheref S.; Perriman, Adam W.; L. Ross Anderson, J.; Mann, Stephen

doi:10.1021/acssynbio.7b00306.s001

Gene-Mediated Chemical Communication in Synthetic Protocell Communities

journal contribution

posted on 2017-11-01, 00:00 authored by T-Y. Dora Tang, Dario Cecchi, Giorgio Fracasso, Davide Accardi, Angelique Coutable-Pennarun, Sheref S. Mansy, Adam W. Perriman, J. L. Ross Anderson, Stephen Mann

A gene-directed chemical communication pathway between synthetic protocell signaling transmitters (lipid vesicles) and receivers (proteinosomes) was designed, built and tested using a bottom-up modular approach comprising small molecule transcriptional control, cell-free gene expression, porin-directed efflux, substrate signaling, and enzyme cascade-mediated processing.

Gene-Mediated Chemical Communication in Synthetic Protocell Communities

History

Usage metrics

Categories

Keywords

Licence

Exports