American Chemical Society
ja510840v_si_001.pdf (3.29 MB)

Foldecture as a Core Material with Anisotropic Surface Characteristics

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journal contribution
posted on 2015-02-18, 00:00 authored by Sung Hyun Yoo, Taedaehyeong Eom, Sunbum Kwon, Jintaek Gong, Jin Kim, Sung June Cho, Russell W. Driver, Yunho Lee, Hyungjun Kim, Hee-Seung Lee
The synthesis of microscale, polyhedrally shaped, soft materials with anisotropic surface functionality by a bottom-up approach remains a significant challenge. Herein we report a microscale molecular architecture (foldecture) with facet-dependent surface characteristics that can potentially serve as a well-defined catalytic template. Rhombic rod shaped foldectures with six facets were obtained by the aqueous self-assembly of helical β-peptide foldamers with a C-terminal carboxylic acid. An analysis of the molecular packing by X-ray diffraction revealed that carboxylic acid groups were exposed exclusively on the two (001) rhombic facets due to antiparallel packing of the helical peptides. A surface energy calculation by molecular dynamics simulation was performed to provide a plausible explanation for the development of anisotropy during foldecture formation. The expected facet-selective surface properties of the foldecture were experimentally confirmed by selective deposition of metal nanoparticles on the (001) facets, leading to a new class of sequentially constructed, heterogeneous “foldecture core” materials.