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Fluorination of Flavones and Chromones Using Elemental Fluorine

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journal contribution
posted on 15.08.2014, 00:00 by Inna Vints, Shlomo Rozen
Flavonoids are abundant micronutrients in our diet, possessing various biological activities. Fluorine was successfully added across the double bond of various flavones and chromones. The difluoro derivative products were easily dehydrofluorinated to form the corresponding 3-fluoroflavones and 3-fluorochromones.