American Chemical Society
ol026285x_si_001.pdf (2.07 MB)

First Total Synthesis of Natural 6-Epiplakortolide E

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journal contribution
posted on 2002-07-04, 00:00 authored by Mankil Jung, Jungyeob Ham, Jueun Song
Natural 6-epiplakortolide E was first synthesized from readily available 1-bromo-10-phenyldecane in 10 steps by using singlet oxygen-mediated Diels−Alder reaction to form cyclic peroxide followed by a directed iodolactonization to give the peroxylactone core.