Finding the Perfect Match: Halogen vs Hydrogen Bonding
journal contributionposted on 07.10.2015, 00:00 by Tanya Shirman, Meital Boterashvili, Meital Orbach, Dalia Freeman, Linda J. W. Shimon, Michal Lahav, Milko E. van der Boom
The prediction of supramolecular structures involving different weak interactions is challenging. In this study, single-atom modifications to the molecular structure allow us to address their hierarchy. The resulting series of unimolecular assemblies are mainly based on halogen bonding (XB), hydrogen bonding (HB), or a combination of both. By varying the XB donor (F, Cl, Br, and I) and the XB and HB acceptors (pyridine vs pyridine-N-oxide) we can control the primary motifs directing the structure.