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Fecal Excretion of Perfluoroalkyl and Polyfluoroalkyl Substances in Pets from New York State, United States
journal contribution
posted on 2020-02-05, 13:11 authored by Jing Ma, Hongkai Zhu, Kurunthachalam KannanHuman
exposure to per- and polyfluoroalkyl substances (PFASs) continues
to be a concern. Little is known about their toxicokinetics, particularly
with regard to fecal excretion of PFASs. Because pets are sentinels
of human exposure to environmental contaminants, analysis of PFASs
in pet feces can provide information about rates of excretion of these
chemicals. In this study, 15 PFASs were measured in cat and dog feces
collected from the Albany area of New York State. All PFASs except
perfluorodecanesulfonate and perfluoroheptanoic acid were found in
cat and dog feces. The sum concentrations of 13 PFASs (∑PFAS)
varied between 21.6 and 474 (mean: 85.4 ± 94.5) ng/g dry weight
for dogs, which were slightly higher than those found for cats (range:
18.0–165 ng/g dry weight, mean: 54.7 ± 26.9 ng/g dry
weight). Long-chain perfluorocarboxylic acids with 9–12 carbons
(perfluorononanoic acid, perfluorodecanoic acid, perfluoroundecanoic
acid, and perfluorododecanoic acid) were predominant in pet feces.
Perfluorooctanesulfonate and its precursors were found at low concentrations.
Fecal excretion rates of PFASs in cats and dogs were found to be similar.
The estimated daily fecal excretion suggested that both dogs and cats
are exposed to some PFASs at doses above the provisional minimum risk
level recommended for humans.