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FeCl3‑Mediated Radical Tandem Reactions of 3‑Benzyl-2-oxindoles with Styrene Derivatives for the Stereoselective Synthesis of Spirocyclohexene Oxindoles

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journal contribution
posted on 07.03.2016, 18:20 by Hong-Ru Wu, Liang Cheng, De-Long Kong, Hong-Yan Huang, Chun-Ling Gu, Li Liu, Dong Wang, Chao-Jun Li
A novel FeCl3-mediated reaction of 3-benzyl-2-oxindoles with styrene derivatives was developed. The reaction provided spirocyclohexene oxindoles in good yields and excellent diastereo­selectivities via a tandem radical addition/cyclization process.

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