ol2030982_si_001.pdf (1.74 MB)

Facile Synthesis of Azaarene-Substituted 3-Hydroxy-2-oxindoles via Brønsted Acid Catalyzed sp3 C–H Functionalization

Download (1.74 MB)
journal contribution
posted on 03.02.2012, 00:00 by Rui Niu, Jian Xiao, Tao Liang, Xingwei Li
Brønsted acid catalyzed functionalization of sp3 C–H bonds in 2-methyl azaarenes has been achieved in the reaction with isatins. This method provides facile synthesis of biologically important azaarene-substituted 3-hydroxy-2-oxindoles in one step in moderate to good yields.

History