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Facile Metal-Assisted Hydrolysis of a Urethane

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journal contribution
posted on 06.11.2001, 00:00 by T. Ross Kelly, Marta Cavero, Yajun Zhao
Kinetic studies demonstrate that it is possible to achieve large rate enhancements (2 × 104) for the hydrolysis of a urethane group by using metal-bound water or hydroxide as the nucleophile.