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Fabrication of Highly Uniform Gel Coatings by the Conversion of Surface-Anchored Metal–Organic Frameworks
journal contribution
posted on 2014-01-08, 00:00 authored by Manuel Tsotsalas, Jinxuan Liu, Beatrix Tettmann, Sylvain Grosjean, Artak Shahnas, Zhengbang Wang, Carlos Azucena, Matthew Addicoat, Thomas Heine, Joerg Lahann, Jörg Overhage, Stefan Bräse, Hartmut Gliemann, Christof WöllWe report the fabrication of 3D,
highly porous, covalently bound
polymer films of homogeneous thickness. These surface-bound gels combine
the advantages of metal–organic framework (MOF) materials,
namely, the enormous flexibility and the large size of the maximum
pore structures and, in particular, the possibility to grow them epitaxially
on modified substrates, with those of covalently connected gel materials,
namely, the absence of metal ions in the deposited material, a robust
framework consisting of covalent bonds, and, most importantly, pronounced
stability under biological conditions. The conversion of a SURMOF
(surface-mounted MOF) yields a surface-grafted gel. These SURGELs
can be loaded with bioactive compounds and applied as bioactive coatings
and provide a drug-release platform in in vitro cell culture studies.